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Restiva® é indicado no tratamento de dor moderada a forte intensidade (quando é necessário terapia contínua com opioide para obter analgesia adequada). Edmond J Restivo. Eligible patients fulfilled the following criteria: 18 to 80 years of age; clinical diagnosis of. Uses for Buprenorphine Pain. Routine consumption of these sweeteners may also lead to a higher risk of cardiometabolic disease. Analgesic; opiate partial agonist.